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Proceedings Paper

Microfluidic particle manipulation using high frequency surface acoustic waves (Conference Presentation)
Author(s): Ye Ai

Paper Abstract

Precise manipulation of particles and biological cells is an essential process in various biomedical research fields, industrial and clinical applications, which remains a very active research area in microfluidics. Among various force fields applied for microfluidic manipulations, acoustic waves have superior propagating properties in solids and fluids, which can readily enable non-contact cell manipulation in long operating distances. In addition, acoustic fields are advantageous to high power laser beams for non-contact optical tweezing in terms of biocompatibility, throughput and setup simplicity. Exploiting acoustic waves for fluid and cell manipulation in microfluidics has led to a newly emerging research area, acoustofluidics. In this presentation, I will talk about particle and cell manipulation in microfluidics using high frequency surface acoustic waves (SAW). In particular, I will discuss a unique design of a focused IDT (FIDT) structure, which is able to generate a highly localized SAW field on the order of 20 µm wide. This highly focused acoustic beam has an effective manipulation area size that is comparable to individual micron-sized particles. Here, I demonstrate the use of this highly localized SAW field for single particle level sorting using sub-millisecond pulses and selective capture of particles. Based on our research studies on acoustic particle manipulation, I envision that the merging of acoustics and microfluidics could enable various particle and cell manipulations needed in microfluidic applications.

Paper Details

Date Published: 19 April 2017
PDF: 1 pages
Proc. SPIE 10061, Microfluidics, BioMEMS, and Medical Microsystems XV, 100610G (19 April 2017); doi: 10.1117/12.2256276
Show Author Affiliations
Ye Ai, Singapore Univ. of Technology & Design (Singapore)

Published in SPIE Proceedings Vol. 10061:
Microfluidics, BioMEMS, and Medical Microsystems XV
Bonnie L. Gray; Holger Becker, Editor(s)

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