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Proceedings Paper

Ten years of biophotonics single-photon SPAD imager applications: retrospective and outlook
Author(s): Claudio Bruschini; Harald Homulle; Edoardo Charbon
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Paper Abstract

SPAD (single-photon avalanche diode) arrays are single-photon imagers that can provide unparalleled timeresolved sensing performance. Since their inception in standard CMOS technologies (2003), a host of architectures and target applications have been explored, ranging from simple pixel arrays, with off-chip data processing electronics, to fully integrated “smart” imagers with in-pixel time-stamping electronics and/or on-chip data processing fabric. Applications include (endoscopic) FLIM, (multi-beam multiphoton) FLIM-FRET, SPIMFCS, time-resolved Raman, NIROT, super-resolution microscopy, and PET, to name a few. We will review some representative sensors and applications, the corresponding challenges, and provide an outlook on the future of this fascinating technology

Paper Details

Date Published: 21 February 2017
PDF: 21 pages
Proc. SPIE 10069, Multiphoton Microscopy in the Biomedical Sciences XVII, 100691S (21 February 2017); doi: 10.1117/12.2256247
Show Author Affiliations
Claudio Bruschini, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Harald Homulle, Technische Univ. Delft (Netherlands)
Edoardo Charbon, Ecole Polytechnique Fédérale de Lausanne (Switzerland)
Technische Univ. Delft (Netherlands)

Published in SPIE Proceedings Vol. 10069:
Multiphoton Microscopy in the Biomedical Sciences XVII
Ammasi Periasamy; Peter T. C. So; Karsten König; Xiaoliang S. Xie, Editor(s)

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