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Proceedings Paper

Broadband coherent Raman imaging as a potential diagnostic aid for histopathology (Conference Presentation)

Paper Abstract

We will report on application of broadband coherent anti-Stokes Raman scattering microscopy1 to chemical mapping and characterization of resected prostate sections. While incidence of prostate cancer is very high, only a small fraction of prostate tumors will progress to advanced, metastatic disease and become dangerous, but prostatectomy and follow-on treatment have many undesirable potential side effects. Thus, it is important to predict which tumors will progress and which should be removed, but there is currently no highly reliable way to make such predictions. We will present a retrospective coherent Raman imaging study resected prostate sections focusing on locating tissue regions that present the highest diagnostic value with respect to lethal vs indolent disease. We intend that this provide a guide to optimal spectral sampling of these tissues to address this important clinical problem.

Paper Details

Date Published: 24 April 2017
PDF: 1 pages
Proc. SPIE 10069, Multiphoton Microscopy in the Biomedical Sciences XVII, 100690P (24 April 2017); doi: 10.1117/12.2256243
Show Author Affiliations
Marcus T. Cicerone, National Institute of Standards and Technology (United States)
Charles H. Camp Jr., National Institute of Standards and Technology (United States)

Published in SPIE Proceedings Vol. 10069:
Multiphoton Microscopy in the Biomedical Sciences XVII
Ammasi Periasamy; Peter T. C. So; Karsten König; Xiaoliang S. Xie, Editor(s)

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