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Proceedings Paper

Quantification of hemoglobin and its derivatives in oral cancer diagnosis by diffuse reflectance spectroscopy
Author(s): Udayakumar Kaniyappan; Einstein Gnanatheepam; Prakasarao Aruna; Koteeswaran Dornadula; Singaravelu Ganesan
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Paper Abstract

Cancer is one of the most common threat to human beings and it increases at an alarming level around the globe. In recent years, due to the advancements in opto-electronic technology, various optical spectroscopy techniques have emerged to assess the photophysicochemical and morphological conditions of normal and malignant tissues in micro as well as in macroscopic scale. In this regard, diffuse reflectance spectroscopy is considered to be the simplest, cost effective and rapid technique in diagnosis of cancerous tissues. In the present study, the hemoglobin concentration in normal and cancerous oral tissues was quantified and subsequent statistical analysis has been carried out to verify the diagnostic potentiality of the technique.

Paper Details

Date Published: 17 February 2017
PDF: 6 pages
Proc. SPIE 10060, Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 100601F (17 February 2017); doi: 10.1117/12.2255874
Show Author Affiliations
Udayakumar Kaniyappan, Univ. of Maryland, College Park (United States)
Einstein Gnanatheepam, Anna Univ., Chennai (India)
Prakasarao Aruna, Anna Univ., Chennai (India)
Koteeswaran Dornadula, Meenakshi Ammal Dental College & Hospital (India)
Singaravelu Ganesan, Anna Univ., Chennai (India)

Published in SPIE Proceedings Vol. 10060:
Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis
Robert R. Alfano; Stavros G. Demos, Editor(s)

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