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Proceedings Paper

The study on the parallel processing based time series correlation analysis of RBC membrane flickering in quantitative phase imaging
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Paper Abstract

Not only static characteristics but also dynamic characteristics of the red blood cell (RBC) contains useful information for the blood diagnosis. Quantitative phase imaging (QPI) can capture sample images with subnanometer scale depth resolution and millisecond scale temporal resolution. Various researches have been used QPI for the RBC diagnosis, and recently many researches has been developed to decrease the process time of RBC information extraction using QPI by the parallel computing algorithm, however previous studies are interested in the static parameters such as morphology of the cells or simple dynamic parameters such as root mean square (RMS) of the membrane fluctuations. Previously, we presented a practical blood test method using the time series correlation analysis of RBC membrane flickering with QPI. However, this method has shown that there is a limit to the clinical application because of the long computation time. In this study, we present an accelerated time series correlation analysis of RBC membrane flickering using the parallel computing algorithm. This method showed consistent fractal scaling exponent results of the surrounding medium and the normal RBC with our previous research.

Paper Details

Date Published: 21 February 2017
PDF: 8 pages
Proc. SPIE 10074, Quantitative Phase Imaging III, 100741T (21 February 2017); doi: 10.1117/12.2253458
Show Author Affiliations
Minsuk Lee, Osong Medical Innovation Foundation (Korea, Republic of)
Youngjae Won, Osong Medical Innovation Foundation (Korea, Republic of)
Byungjun Park, Osong Medical Innovation Foundation (Korea, Republic of)
Seungrag Lee, Osong Medical Innovation Foundation (Korea, Republic of)


Published in SPIE Proceedings Vol. 10074:
Quantitative Phase Imaging III
Gabriel Popescu; YongKeun Park, Editor(s)

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