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Proceedings Paper

Using stereotactic brain atlases for small rodents and nonhuman primates for optrode array customization
Author(s): Ronald W. Boutte; Sam Merlin; Brandon Griffiths; Trent Parry; Steve Blair
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Paper Abstract

As the optogenetic field expands its need to target with high specificity only grows more crucial. This work will show a method for customizing soda-lime glass optrode arrays so that fine structures within the brains of small rodents and nonhuman primates can be optically interrogated below the outer cortical layer. An 8 × 6 array is customized for optrode length (400 μm ), optrode width (75 μm ), optrode pitch (400 μm ), backplane thickness (500 μm ), and overall form factor (3.45 mm × 2.65 mm ). The 400 μm long optrode is capable of illuminating the cortical Layer IV of rhesus macaque ( Macaca Fascicularis ) and the motor cortex of small mice ( Mus Musculus ).

Paper Details

Date Published: 20 February 2017
PDF: 5 pages
Proc. SPIE 10052, Optogenetics and Optical Manipulation, 1005204 (20 February 2017); doi: 10.1117/12.2251601
Show Author Affiliations
Ronald W. Boutte, The Univ. of Utah (United States)
Northrop Grumman Corp. (United States)
Sam Merlin, The Univ. of Utah (United States)
Brandon Griffiths, Northrop Grumman Corp. (United States)
Trent Parry, The Univ. of Utah (United States)
Steve Blair, The Univ. of Utah (United States)

Published in SPIE Proceedings Vol. 10052:
Optogenetics and Optical Manipulation
Samarendra K. Mohanty; Nitish V. Thakor; E. Duco Jansen, Editor(s)

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