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Proceedings Paper

Optical coherence tomography for image-guided dermal filler injection and biomechanical evaluation
Author(s): Manmohan Singh; Shang Wang; Richard W. Yee; Zhaolong Han; Salavat R. Aglyamov; Kirill V. Larin
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Paper Abstract

Dermal fillers are a very popular anti-ag ing treatment with estimated sales in the billions of dollars and millions of procedures performed. As the aging population continues to grow, these figures are only e xpected to increase. Dermal fillers have various compositions depending on their intended applicati on. Reactions to dermal fillers can be severe, such as ischemic events and filler migration to the eyes. Howe ver, these adverse reactions are rare. Nevertheless, the capability to perform imag e-guided filler injections would minimize th e risk of such reacti ons. In addition, the biomechanical properties of various fillers have been evalua ted, but there has been no investigation on the effects of filler on the biomechanical properties of skin. In this work, we utilize optical cohe rence tomography (OCT) for visualizing dermal filler injections with micrometer-scale sp atial resolution. In addition, we utilize noncontact optical coherence elastography (OCE) to quantify the changes in the biomechan ical properties of pig skin after the dermal filler injections. OCT was successfully able to visualize the dermal filler injecti on process, and OCE showed that the viscoelasticity of the pig skin was increased locally at the filler injection sites. OCT may be able to provide real-time image guidance in 3D, and when combined with functional OCT techniques such as optical microangiography, could be used to avoid blood vessels during the injection.

Paper Details

Date Published: 6 February 2017
PDF: 8 pages
Proc. SPIE 10037, Photonics in Dermatology and Plastic Surgery, 100370W (6 February 2017); doi: 10.1117/12.2251541
Show Author Affiliations
Manmohan Singh, Univ. of Houston (United States)
Shang Wang, Baylor College of Medicine (United States)
Richard W. Yee, SeeFit Inc. (United States)
Zhaolong Han, Univ. of Houston (United States)
Salavat R. Aglyamov, The Univ. of Texas at Austin (United States)
Kirill V. Larin, Univ. of Houston (United States)
Baylor College of Medicine (United States)

Published in SPIE Proceedings Vol. 10037:
Photonics in Dermatology and Plastic Surgery
Bernard Choi; Haishan Zeng; Nikiforos Kollias, Editor(s)

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