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Proceedings Paper

Short pulse laser induced thermo-elastic deformation imaging
Author(s): Tianshi Wang; Tom Pfeiffer; Min Wu; Wolfgang Wieser; Wolfgang Draxinger; Antonius F. W. van der Steen; Robert Huber; Gijs van Soest
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Paper Abstract

Absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue, i.e. a sub-micrometer scale displacement happens within a couple of microseconds. In this study, we initially investigate the depth-resolved deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. Functional images can be reconstructed based on the detected deformation, which enables a new imaging modality called thermo-elastic deformation imaging (TDI). Our results show that the associated displacement is related to the optical absorption of the short laser pulses. The TDI images can provide tissue type information in addition to the conventional OCT images.

Paper Details

Date Published: 15 February 2017
PDF: 4 pages
Proc. SPIE 10062, Optical Interactions with Tissue and Cells XXVIII, 100620C (15 February 2017); doi: 10.1117/12.2251502
Show Author Affiliations
Tianshi Wang, Erasmus MC (Netherlands)
Tom Pfeiffer, Univ. zu Lübeck (Germany)
Min Wu, Erasmus MC (Netherlands)
Wolfgang Wieser, Ludwig-Maximilians-Univ. München (Germany)
Wolfgang Draxinger, Univ. zu Lübeck (Germany)
Antonius F. W. van der Steen, Erasmus MC (Netherlands)
Shenzhen Institutes of Advanced Technology (China)
Delft Univ. of Technology (Netherlands)
Robert Huber, Univ. zu Lübeck (Germany)
Gijs van Soest, Erasmus MC (Netherlands)

Published in SPIE Proceedings Vol. 10062:
Optical Interactions with Tissue and Cells XXVIII
E. Duco Jansen; Hope Thomas Beier, Editor(s)

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