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Proceedings Paper

Through-skull vasculature assessment using fluorescence brain imaging on murine models at around 800 nm
Author(s): Hanh N. D. Le; Yung-Tian A. Gau; Arman Rahmim; Dean F. Wong; Dwight E. Bergles; Jin U. Kang
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Paper Abstract

We describe a scanning near-infrared fluorescence imager for through-skull non-invasive brain imaging on live murine models. The captured photoluminescence feature through scattering media was enhanced using a high sensitivity scientific CMOS sensor with the obtained spatial resolution of 15.63 μm, depth of field of 5 mm and an average local signal-to-noise ratio of 37.5 dB.

Paper Details

Date Published: 8 February 2017
PDF: 7 pages
Proc. SPIE 10051, Neural Imaging and Sensing, 100510M (8 February 2017); doi: 10.1117/12.2250240
Show Author Affiliations
Hanh N. D. Le, Johns Hopkins Univ. (United States)
Yung-Tian A. Gau, Johns Hopkins Univ. (United States)
Arman Rahmim, Johns Hopkins Univ. (United States)
Dean F. Wong, Johns Hopkins Univ. (United States)
Dwight E. Bergles, Johns Hopkins Univ. (United States)
Jin U. Kang, Johns Hopkins Univ. (United States)

Published in SPIE Proceedings Vol. 10051:
Neural Imaging and Sensing
Qingming Luo; Jun Ding, Editor(s)

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