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Proceedings Paper

Preliminary results of miniaturized and robust ultrasound guided diffuse optical tomography system for breast cancer detection
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Paper Abstract

According to the World Health Organization, breast cancer is the most common cancer among women worldwide, claiming the lives of hundreds of thousands of women each year. Near infrared diffuse optical tomography (DOT) has demonstrated a great potential as an adjunct modality for differentiation of malignant and benign breast lesions and for monitoring treatment response of patients with locally advanced breast cancers. The path toward commercialization of DOT techniques depends upon the improvement of robustness and user-friendliness of this technique in hardware and software. In the past, our group have developed three frequency domain prototype systems which were used in several clinical studies. In this study, we introduce our newly under development US-guided DOT system which is being improved in terms of size, robustness and user friendliness by several custom electronic and mechanical design. A new and robust probe designed to reduce preparation time in clinical process. The processing procedure, data selection and user interface software also updated. With all these improvements, our new system is more robust and accurate which is one step closer to commercialization and wide use of this technology in clinical settings. This system is aimed to be used by minimally trained user in the clinical settings with robust performance. The system performance has been tested in the phantom experiment and initial results are demonstrated in this study. We are currently working on finalizing this system and do further testing to validate the performance of this system. We are aiming toward use of this system in clinical setting for patients with breast cancer.

Paper Details

Date Published: 17 February 2017
PDF: 6 pages
Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100590F (17 February 2017); doi: 10.1117/12.2250034
Show Author Affiliations
Hamed Vavadi, Univ. of Connecticut (United States)
Atahar Mostafa, Washington Univ. in St. Louis (United States)
Jinglong Li, Univ. of Connecticut (United States)
Feifei Zhou, Univ. of Connecticut (United States)
Shihab Uddin, Washington Univ. in St. Louis (United States)
Chen Xu, New York City College of Technology (United States)
Quing Zhu, Washington Univ. in St. Louis (United States)

Published in SPIE Proceedings Vol. 10059:
Optical Tomography and Spectroscopy of Tissue XII
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca; Robert R. Alfano, Editor(s)

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