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Proceedings Paper

Au particle formation on the electron beam induced membrane
Author(s): Seong Soo Choi; Myoung Jin Park; Chul Hee Han; Sae-Joong Oh; Sung-In Kim; Nam Kyou Park; Doo-Jae Park; Soo Bong Choi; Yong-Sang Kim
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Paper Abstract

Recently the single molecules such as protein and deoxyribonucleic acid (DNA) have been successfully characterized by using a portable solidstate nanopore (MinION) with an electrical detection technique. However, there have been several reports about the high error rates of the fabricated nanopore device, possibly due to an electrical double layer formed inside the pore channel. The current DNA sequencing technology utilized is based on the optical detection method. In order to utilize the current optical detection technique, we will present the formation of the Au nano-pore with Au particle under the various electron beam irradiations. In order to provide the diffusion of Au atoms, a 2 keV electron beam irradiation has been performed During electron beam irradiations by using field emission scanning electron microscopy (FESEM), Au and C atoms would diffuse together and form the binary mixture membrane. Initially, the Au atoms diffused in the membrane are smaller than 1 nm, below the detection limit of the transmission electron microscopy (TEM), so that we are unable to observe the Au atoms in the formed membrane. However, after several months later, the Au atoms became larger and larger with expense of the smaller particles: Ostwald ripening. Furthermore, we also observe the Au crystalline lattice structure on the binary Au-C membrane. The formed Au crystalline lattice structures were constantly changing during electron beam imaging process due to Spinodal decomposition; the unstable thermodynamic system of Au-C binary membrane. The fabricated Au nanopore with an Au nanoparticle can be utilized as a single molecule nanobio sensor.

Paper Details

Date Published: 23 February 2017
PDF: 7 pages
Proc. SPIE 10081, Frontiers in Biological Detection: From Nanosensors to Systems IX, 1008103 (23 February 2017); doi: 10.1117/12.2249534
Show Author Affiliations
Seong Soo Choi, Sun Moon Univ. (Korea, Republic of)
Myoung Jin Park, Sun Moon Univ. (Korea, Republic of)
Chul Hee Han, Sun Moon Univ. (Korea, Republic of)
Sae-Joong Oh, Sun Moon Univ. (Korea, Republic of)
Sung-In Kim, National Nanofabrication Ctr. (Korea, Republic of)
Nam Kyou Park, Seoul National Univ. (Korea, Republic of)
Doo-Jae Park, Hallym Univ. (Korea, Republic of)
Soo Bong Choi, Inchon National Univ. (Korea, Republic of)
Yong-Sang Kim, SungKyunKwan Univ. (Korea, Republic of)

Published in SPIE Proceedings Vol. 10081:
Frontiers in Biological Detection: From Nanosensors to Systems IX
Amos Danielli; Benjamin L. Miller; Sharon M. Weiss, Editor(s)

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