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Method for the determination of cobalt from biological products with graphite furnace atomic absorption spectrometer
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Paper Abstract

Cobalt is a chemical element with symbol Co and atomic number 27 and atomic weight 58.93. 59 Co is the only stable cobalt isotope and the only isotope to exist naturally on Earth. Cobalt is the active center of coenzymes called cobalamin or cyanocobalamin the most common example of which is vitamin B12. Vitamin B12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system in the form of fatigue, depression and poor memory or even mania and psychosis. In order to study the degree of deficiency of the population with Co or the correctness of treatment with vitamin B12, a modern optoelectronic method for the determination of metals and metalloids from biological samples has been developed, Graphite Furnace – Atomic Absorption Spectrometer (GF– AAS) method is recommended. The technique is based on the fact that free atoms will absorb light at wavelengths characteristic of the element of interest. Free atoms of the chemical element can be produced from samples by the application of high temperatures. The system GF-AAS Varian used as biological samples, blood or urine that followed the digest of the organic matrix. For the investigations was used a high – performance GF-AAS with D2 – background correction system and a transversely heated graphite atomizer. As result of the use of the method are presented the concentration of Co in the blood or urine of a group of patient in Bucharest. The method is sensitive, reproducible relatively easy to apply, with a moderately costs.

Paper Details

Date Published: 14 December 2016
PDF: 4 pages
Proc. SPIE 10010, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies VIII, 100103I (14 December 2016); doi: 10.1117/12.2245311
Show Author Affiliations
Oana-Liliana Zamfir, Univ. Politehnica of Bucharest (Romania)
Mihai Ionică, Univ. Politehnica of Bucharest (Romania)
Ctr. for Military Medical Scientific Research (Romania)
Genica Caragea, Ctr. for Military Medical Scientific Research (Romania)
Clininical Emergency Hospital Bucharest (Romania)
Simona Radu, Univ. Politehnica of Bucharest (Romania)
Marian Vlădescu, Univ. Politehnica of Bucharest (Romania)

Published in SPIE Proceedings Vol. 10010:
Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies VIII
Marian Vladescu; Cornel T. Panait; Razvan Tamas; George Caruntu; Ionica Cristea, Editor(s)

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