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Proceedings Paper

Fluorometric biosniffer (biochemical gas sensor) for breath acetone as a volatile indicator of lipid metabolism
Author(s): Kohji Mitsubayashi; Po-Jen Chien; Ming Ye; Takuma Suzuki; Koji Toma; Takahiro Arakawa
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Paper Abstract

A fluorometric acetone biosniffer (biochemical gas sensor) for assessment of lipid metabolism utilizing reverse reaction of secondary alcohol dehydrogenase was constructed and evaluated. The biosniffer showed highly sensitivity and selectivity for continuous monitoring of gaseous acetone. The measurement of breath acetone concentration during fasting and aerobic exercise were also investigated. The acetone biosniffer provides a novel analytical tool for noninvasive evaluation of human lipid metabolism and it is also expected to use for the clinical and physiological applications such as monitoring the progression of diabetes.

Paper Details

Date Published: 24 November 2016
PDF: 2 pages
Proc. SPIE 10013, SPIE BioPhotonics Australasia, 100131T (24 November 2016); doi: 10.1117/12.2244660
Show Author Affiliations
Kohji Mitsubayashi, Tokyo Medical and Dental Univ. (Japan)
Po-Jen Chien, Tokyo Medical and Dental Univ. (Japan)
Ming Ye, Tokyo Medical and Dental Univ. (Japan)
Takuma Suzuki, Tokyo Medical and Dental Univ. (Japan)
Koji Toma, Tokyo Medical and Dental Univ. (Japan)
Takahiro Arakawa, Tokyo Medical and Dental Univ. (Japan)

Published in SPIE Proceedings Vol. 10013:
SPIE BioPhotonics Australasia
Mark R. Hutchinson; Ewa M. Goldys, Editor(s)

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