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Proceedings Paper

Thermophoretic trapping and manipulation of single molecules
Author(s): Marco Braun; Tobias Thalheim; Katrin Günther; Michael Mertig; Frank Cichos
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Paper Abstract

We demonstrate the long time trapping of single DNA molecules in liquids by feedback driven dynamic temperature fields. By spatially and temporally varying the temperature at a plasmonic nanostructure, thermophoretic drifts are induced that are used to trap single nano-objects. A feedback controlled switching of local temperature fields allows us to confine the motion of a single DNA molecule for minutes. The DNA conformation and conformation dynamics are analyzed in terms of a principle component analysis. Current results are in agreement with previous measurements in thermal equilibrium and suggest only a weak influence of the inhomogeneous temperature rise on the structure and dynamics in the trap.

Paper Details

Date Published: 23 November 2016
PDF: 8 pages
Proc. SPIE 9922, Optical Trapping and Optical Micromanipulation XIII, 99220Z (23 November 2016); doi: 10.1117/12.2239481
Show Author Affiliations
Marco Braun, Univ. Leipzig (Germany)
Tobias Thalheim, Univ. Leipzig (Germany)
Katrin Günther, TU Dresden (Germany)
Michael Mertig, TU Dresden (Germany)
Kurt-Schwabe-Institut für Mess- und Sensortechnik e.V. (Germany)
Frank Cichos, Univ. Leipzig (Germany)
Princeton Univ. (United States)

Published in SPIE Proceedings Vol. 9922:
Optical Trapping and Optical Micromanipulation XIII
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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