
Proceedings Paper
Portable fluorescence meter with reference backscattering channelFormat | Member Price | Non-Member Price |
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$17.00 | $21.00 |
Paper Abstract
Methods based on fluorescence and backscattering are intensively used for determination of the advanced glycation end
products (AGE) concentration in the biological tissues. There are strong correlation between the AGE concentration and
the severity of such diseases like diabetes, coronary heart disease and renal failure. This fact can be used for diagnostic
purposes in medical applications. Only few investigations in this area can be useful for development of portable and
affordable in vivo AGE meter because the most of them are oriented on using spectrometers. In this study we describe
the design and the results of tests on volunteers of portable fluorescence meter based on two photodiodes. One channel of
such fluorimeter is used for measurement of the autofluorescence (AF) intensity, another one – for the intensity of
elastically scattered radiation, which can be used as a reference. This reference channel is proposed for normalization of
the skin autofluorescence signal to the human skin photo type. The fluorimeter, that was developed is relatively compact
and does not contain any expensive optical and electronic components. The experimental results prove that proposed tool
can be used for the AGE estimation in human skin.
Paper Details
Date Published: 26 September 2016
PDF: 8 pages
Proc. SPIE 9961, Reflection, Scattering, and Diffraction from Surfaces V, 99610C (26 September 2016); doi: 10.1117/12.2237135
Published in SPIE Proceedings Vol. 9961:
Reflection, Scattering, and Diffraction from Surfaces V
Leonard M. Hanssen, Editor(s)
PDF: 8 pages
Proc. SPIE 9961, Reflection, Scattering, and Diffraction from Surfaces V, 99610C (26 September 2016); doi: 10.1117/12.2237135
Show Author Affiliations
Dmitriy V. Kornilin, Samara National Research Univ. (Russian Federation)
Vladimir N. Grishanov, Samara National Research Univ. (Russian Federation)
Vladimir N. Grishanov, Samara National Research Univ. (Russian Federation)
Valery P. Zakharov, Samara National Research Univ. (Russian Federation)
Dmitriy S. Burkov, Samara National Research Univ. (Russian Federation)
Dmitriy S. Burkov, Samara National Research Univ. (Russian Federation)
Published in SPIE Proceedings Vol. 9961:
Reflection, Scattering, and Diffraction from Surfaces V
Leonard M. Hanssen, Editor(s)
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