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Proceedings Paper

Regeneration of titanium oxide nano-coated long-period grating biosensor
Author(s): M. Dominik; J. Niedziółka-Jönsson; E. Roźniecka; Ł. Wachnicki; M. Godlewski; P. Mikulic; Wojtek J. Bock; M. Śmietana
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Paper Abstract

This work presents an application of sodium hydroxide (NaOH) as an effective method for regeneration of titanium oxide (TiOx) nano-coated long-period grating (LPG) biosensor. Below 100 nm in thickness TiOx coating was deposited with atomic layer deposition (ALD) method on LPGs for enhancing their refractive index sensitivity up to 2912 nm/RIU in RI range 1.33-1.36 RIU. Next, the sensors were biofunctionalized in order to immobilize receptor (biotin) on their surface and used for selective avidin detection. After successful biofunctionalization process and avidin detection the sensors were washed in NaOH and biofunctionalized again. The proposed method for recovering the sensor does not cause decrease in its functional properties. As a result of the applied procedure the biosensor was fully regenerated.

Paper Details

Date Published: 30 May 2016
PDF: 4 pages
Proc. SPIE 9916, Sixth European Workshop on Optical Fibre Sensors, 99160Z (30 May 2016); doi: 10.1117/12.2236878
Show Author Affiliations
M. Dominik, Warsaw Univ. of Technology (Poland)
J. Niedziółka-Jönsson, Institute of Physical Chemistry (Poland)
E. Roźniecka, Institute of Physical Chemistry (Poland)
Ł. Wachnicki, Institute of Physics (Poland)
M. Godlewski, Institute of Physics (Poland)
P. Mikulic, Univ. du Québec en Outaouais (Canada)
Wojtek J. Bock, Univ. du Québec en Outaouais (Canada)
M. Śmietana, Warsaw University of Technology (Poland)

Published in SPIE Proceedings Vol. 9916:
Sixth European Workshop on Optical Fibre Sensors
Elfed Lewis, Editor(s)

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