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Proceedings Paper

Photodynamic therapy with laser scanning mode of tumor irradiation
Author(s): Oksana Chepurna; Irina Shton; Vladimir Kholin; Valerii Voytsehovich; Viacheslav Popov; Sergii Pavlov; Nikolai Gamaleia; Waldemar Wójcik; Maral Zhassandykyzy
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Paper Abstract

In this study we propose a new version of photodynamic therapy performed by laser scanning. The method consists in tumor treatment by a light beam of a small cross section which incrementally moves through the chosen area with a defined delay at each point and repetitively re-scans a zone starting from the initial position. Experimental evaluation of the method in vitro on murine tumor model showed that despite the dose, applied by scanning irradiation mode, was 400 times lower, the tumor inhibition rate conceded to attained with continuous irradiation mode by only 20%.

Paper Details

Date Published: 17 December 2015
PDF: 4 pages
Proc. SPIE 9816, Optical Fibers and Their Applications 2015, 98161F (17 December 2015); doi: 10.1117/12.2229030
Show Author Affiliations
Oksana Chepurna, PSME "Fotonika Plus" (Ukraine)
Irina Shton, Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (Ukraine)
Vladimir Kholin, PSME "Fotonika Plus" (Ukraine)
Valerii Voytsehovich, Institute of Physics (Ukraine)
Viacheslav Popov, State Scientific Research Institute of Physical Culture and Sports (Ukraine)
Sergii Pavlov, Vinnytsia National Technical Univ. (Ukraine)
Nikolai Gamaleia, Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (Ukraine)
Waldemar Wójcik, Lublin Univ. of Technology (Poland)
Maral Zhassandykyzy, Kazakh National Research Technical Univ. (Kazakhstan)

Published in SPIE Proceedings Vol. 9816:
Optical Fibers and Their Applications 2015
Ryszard S. Romaniuk; Waldemar Wojcik; Andrzej Smolarz, Editor(s)

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