Diagnostically challenging lesions pose a challenge both for the radiological reading and also for current CAD systems. They are not well-defined in both morphology (geometric shape) and kinetics (temporal enhancement) and pose a problem to lesion detection and classification. Their strong phenotypic differences can be visualized by MRI. Radiomics represents a novel approach to achieve a detailed quantification of the tumour phenotypes by analyzing a large number of image descriptors. In this paper, we apply a quantitative radiomics approach based on shape, texture and kinetics tumor features and evaluate it in comparison to a reduced-order feature approach in a computer-aided diagnosis system applied to diagnostically challenging lesions.

Date Published: 12 July 2016
PDF: 7 pages
Proc. SPIE 9871, Sensing and Analysis Technologies for Biomedical and Cognitive Applications 2016, 98710H (12 July 2016); doi: 10.1117/12.2228994

Published in SPIE Proceedings Vol. 9871:
Sensing and Analysis Technologies for Biomedical and Cognitive Applications 2016
Liyi Dai; Yufeng Zheng; Henry Chu; Anke D. Meyer-Bäse, Editor(s)