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Proceedings Paper

SERS spectroscopy, electrical recording and intracellular injection in neuronal networks with 3D plasmonic nanoantennas
Author(s): Valeria Caprettini; Gabriele C. Messina; Michele Dipalo; Rosanna La Rocca; Andrea Cerea; Francesco De Angelis
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Paper Abstract

We developed a platform based on 3D plasmonic nanoantennas able to perform different functions with applications in the biological research area. In particular it will be shown how the peculiar geometry of the system plays a fundamental role, leading to a tight interaction with the cellular membrane. Such configuration allows on one side the investigation of extracellular features through enhanced vibrational spectroscopy and electrical recording, and on the other the possibility of intracellular injection by optoporation. In this regard it will be demonstrated how the characteristics of the laser pulse used for exciting the antenna establish the kind of involved phenomena. A dependence of these properties on the metal coating the antenna will be also shown.

Paper Details

Date Published: 9 March 2016
PDF: 7 pages
Proc. SPIE 9740, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XVI, 974002 (9 March 2016); doi: 10.1117/12.2222830
Show Author Affiliations
Valeria Caprettini, Istituto Italiano di Tecnologia (Italy)
Gabriele C. Messina, Istituto Italiano di Tecnologia (Italy)
Michele Dipalo, Istituto Italiano di Tecnologia (Italy)
Rosanna La Rocca, Istituto Italiano di Tecnologia (Italy)
Andrea Cerea, Istituto Italiano di Tecnologia (Italy)
Francesco De Angelis, Istituto Italiano di Tecnologia (Italy)

Published in SPIE Proceedings Vol. 9740:
Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XVI
Alexander Heisterkamp; Peter R. Herman; Michel Meunier; Stefan Nolte, Editor(s)

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