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Proceedings Paper

Brillouin microspectroscopy of nanostructured biomaterials: photonics assisted tailoring mechanical properties
Author(s): Zhaokai Meng; Manish K. Jaiswal; Chandani Chitrakar; Teena Thakur; Akhilesh K. Gaharwar; Vladislav V. Yakovlev
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Paper Abstract

Developing new biomaterials is essential for the next-generation of materials for bioenergy, bioelectronics, basic biology, medical diagnostics, cancer research, and regenerative medicine. Specifically, recent progress in nanotechnology has stimulated the development of multifunctional biomaterials for tissue engineering applications. The physical properties of nanocomposite biomaterials, including elasticity and viscosity, play key roles in controlling cell fate, which underlines therapeutic success. Conventional mechanical tests, including uniaxial compression and tension, dynamic mechanical analysis and shear rheology, require mechanical forces to be directly exerted onto the sample and therefore may not be suitable for in situ measurements or continuous monitoring of mechanical stiffness. In this study, we employ spontaneous Brillouin spectroscopy as a viscoelasticity-specific probing technique. We utilized a Brillouin spectrometer to characterize biomaterial’s microscopic elasticity and correlated those with conventional mechanical tests (e.g., rheology).

Paper Details

Date Published: 23 March 2016
PDF: 8 pages
Proc. SPIE 9737, Synthesis and Photonics of Nanoscale Materials XIII, 97370G (23 March 2016); doi: 10.1117/12.2222816
Show Author Affiliations
Zhaokai Meng, Texas A&M Univ. (United States)
Manish K. Jaiswal, Texas A&M Univ. (United States)
Chandani Chitrakar, Texas A&M Univ. (United States)
Teena Thakur, Texas A&M Univ. (United States)
Akhilesh K. Gaharwar, Texas A&M Univ. (United States)
Vladislav V. Yakovlev, Texas A&M Univ. (United States)

Published in SPIE Proceedings Vol. 9737:
Synthesis and Photonics of Nanoscale Materials XIII
Andrei V. Kabashin; David B. Geohegan; Jan J. Dubowski, Editor(s)

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