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Proceedings Paper

Comparison of stroke infarction between CT perfusion and diffusion weighted imaging: preliminary results
Author(s): Ashrani Aizzuddin Abd. Rahni; Israna Hossain Arka; Kalaivani Chellappan; Shahizon Azura Mukari; Zhe Kang Law; Ramesh Sahathevan
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Paper Abstract

In this paper we present preliminary results of comparison of automatic segmentations of the infarct core, between that obtained from CT perfusion (based on time to peak parameter) and diffusion weighted imaging (DWI). For each patient, the two imaging volumes were automatically co-registered to a common frame of reference based on an acquired CT angiography image. The accuracy of image registration is measured by the overlap of the segmented brain from both images (CT perfusion and DWI), measured within their common field of view. Due to the limitations of the study, DWI was acquired as a follow up scan up to a week after initial CT based imaging. However, we found significant overlap of the segmented brain (Jaccard indices of approximately 0.8) and the percentage of infarcted brain tissue from the two modalities were still fairly highly correlated (correlation coefficient of approximately 0.9). The results are promising with more data needed in future for clinical inference.

Paper Details

Date Published: 29 March 2016
PDF: 7 pages
Proc. SPIE 9788, Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging, 978824 (29 March 2016); doi: 10.1117/12.2218313
Show Author Affiliations
Ashrani Aizzuddin Abd. Rahni, Univ. Kebangsaan Malaysia (Malaysia)
Israna Hossain Arka, Univ. Kebangsaan Malaysia (Malaysia)
Kalaivani Chellappan, Univ. Kebangsaan Malaysia (Malaysia)
Shahizon Azura Mukari, Univ. Kebangsaan Malaysia (Malaysia)
Zhe Kang Law, UKM Medical Ctr., Univ. Kebangsaan Malaysia (Malaysia)
Ramesh Sahathevan, Univ. Kebangsaan Malaysia (Malaysia)

Published in SPIE Proceedings Vol. 9788:
Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

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