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Proceedings Paper

Single molecule force spectroscopy study of y-polyglutamic acid by using atomic force microscopy
Author(s): Parbhej Ahamed; Masaru Kawakami; Hidemitsu Furukawa
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Paper Abstract

γ-PGA is a versatile multi-functional biopolymer possessing much useful biological functionality. Each biological function is associated with specific properties related to various forms of γ-PGA. However, to date, knowledge about the molecular mechanism to control specific structures of γ-PGA under a certain environmental conditions are unknown. In this study, we used single molecule force spectroscopy (SMFS) method to characterize the structure of γ-PGA in two environmental conditions. A water environment or 0.5 M MgCl2 salt solution was used to observe the effect of metal ion on γ-PGA structure at room temperature. The obtained results revealed that γ-PGA exists branched and/or cross-linked structure of γ-PGA in water or MgCl2 salt solution.

Paper Details

Date Published: 16 April 2016
PDF: 5 pages
Proc. SPIE 9802, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016, 98020O (16 April 2016); doi: 10.1117/12.2218040
Show Author Affiliations
Parbhej Ahamed, Yamagata Univ. (Japan)
Masaru Kawakami, Yamagata Univ. (Japan)
Hidemitsu Furukawa, Yamagata Univ. (Japan)

Published in SPIE Proceedings Vol. 9802:
Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2016
Vijay K. Varadan, Editor(s)

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