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Proceedings Paper

In vivo photoacoustic flowmetry in the optical diffusive regime based on saline injection
Author(s): Yong Zhou; Joemini Poudel; Guo Li; Lihong V. Wang
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Paper Abstract

We propose a saline-injection-based method to quantify blood flow velocity in vivo with acoustic-resolution photoacoustic tomography. By monitoring the saline-blood-interface propagating in the blood vessel, we can resolve the flow velocity. In phantom experiments, a root-mean-squared error of prediction of 0.29 mm/s was achieved. By injecting saline into a mouse tail vein covered with 1 mm chicken tissue, we showed that the flow velocity in the tail vein could be measured at depth, which is especially pertinent to monitoring blood flow velocity in patients undergoing intravenous infusion.

Paper Details

Date Published: 15 March 2016
PDF: 7 pages
Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97084U (15 March 2016); doi: 10.1117/12.2217468
Show Author Affiliations
Yong Zhou, Washington Univ. in St. Louis (United States)
Joemini Poudel, Washington Univ. in St. Louis (United States)
Guo Li, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 9708:
Photons Plus Ultrasound: Imaging and Sensing 2016
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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