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Proceedings Paper

Optimization-based reconstruction for reduction of CBCT artifact in IGRT
Author(s): Dan Xia; Zheng Zhang; Pascal Paysan; Dieter Seghers; Marcus Brehm; Peter Munro; Emil Y. Sidky; Charles Pelizzari; Xiaochuan Pan
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Paper Abstract

Kilo-voltage cone-beam computed tomography (CBCT) plays an important role in image guided radiation therapy (IGRT) by providing 3D spatial information of tumor potentially useful for optimizing treatment planning. In current IGRT CBCT system, reconstructed images obtained with analytic algorithms, such as FDK algorithm and its variants, may contain artifacts. In an attempt to compensate for the artifacts, we investigate optimization-based reconstruction algorithms such as the ASD-POCS algorithm for potentially reducing arti- facts in IGRT CBCT images. In this study, using data acquired with a physical phantom and a patient subject, we demonstrate that the ASD-POCS reconstruction can significantly reduce artifacts observed in clinical re- constructions. Moreover, patient images reconstructed by use of the ASD-POCS algorithm indicate a contrast level of soft-tissue improved over that of the clinical reconstruction. We have also performed reconstructions from sparse-view data, and observe that, for current clinical imaging conditions, ASD-POCS reconstructions from data collected at one half of the current clinical projection views appear to show image quality, in terms of spatial and soft-tissue-contrast resolution, higher than that of the corresponding clinical reconstructions.

Paper Details

Date Published: 1 April 2016
PDF: 4 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97834B (1 April 2016); doi: 10.1117/12.2217234
Show Author Affiliations
Dan Xia, The Univ. of Chicago (United States)
Zheng Zhang, The Univ. of Chicago (United States)
Pascal Paysan, Varian Medical Systems, Inc. (Switzerland)
Dieter Seghers, Varian Medical Systems, Inc. (Switzerland)
Marcus Brehm, Varian Medical Systems, Inc. (Switzerland)
Peter Munro, Varian Medical Systems, Inc. (Switzerland)
Emil Y. Sidky, The Univ. of Chicago (United States)
Charles Pelizzari, The Univ. of Chicago (United States)
Xiaochuan Pan, The Univ. of Chicago (United States)

Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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