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Proceedings Paper

Multi-acoustic lens design methodology for a low cost C-scan photoacoustic imaging camera
Author(s): Bhargava Chinni; Zichao Han; Nicholas Brown; Pedro Vallejo; Tess Jacobs; Wayne Knox; Vikram Dogra; Navalgund Rao
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Paper Abstract

We have designed and implemented a novel acoustic lens based focusing technology into a prototype photoacoustic imaging camera. All photoacoustically generated waves from laser exposed absorbers within a small volume get focused simultaneously by the lens onto an image plane. We use a multi-element ultrasound transducer array to capture the focused photoacoustic signals. Acoustic lens eliminates the need for expensive data acquisition hardware systems, is faster compared to electronic focusing and enables real-time image reconstruction. Using this photoacoustic imaging camera, we have imaged more than 150 several centimeter size ex-vivo human prostate, kidney and thyroid specimens with a millimeter resolution for cancer detection. In this paper, we share our lens design strategy and how we evaluate the resulting quality metrics (on and off axis point spread function, depth of field and modulation transfer function) through simulation. An advanced toolbox in MATLAB was adapted and used for simulating a two-dimensional gridded model that incorporates realistic photoacoustic signal generation and acoustic wave propagation through the lens with medium properties defined on each grid point. Two dimensional point spread functions have been generated and compared with experiments to demonstrate the utility of our design strategy. Finally we present results from work in progress on the use of two lens system aimed at further improving some of the quality metrics of our system.

Paper Details

Date Published: 15 March 2016
PDF: 15 pages
Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97081Q (15 March 2016); doi: 10.1117/12.2212933
Show Author Affiliations
Bhargava Chinni, Univ. of Rochester Medical Ctr. (United States)
Zichao Han, Rochester Institute of Technology (United States)
Nicholas Brown, Univ. of Rochester (United States)
Pedro Vallejo, Univ. of Rochester (United States)
Tess Jacobs, Univ. of Rochester (United States)
Wayne Knox, Univ. of Rochester (United States)
Vikram Dogra, Univ. of Rochester Medical Ctr. (United States)
Navalgund Rao, Rochester Institute of Technology (United States)

Published in SPIE Proceedings Vol. 9708:
Photons Plus Ultrasound: Imaging and Sensing 2016
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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