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Proceedings Paper

Quantitative wound healing studies using a portable, low cost, handheld near-infrared optical scanner: preliminary sensitivity and specificity analysis
Author(s): Jiali Lei; Suset Rodriguez; Maanasa Jayachandran; Elizabeth Solis; Stephanie Gonzalez; Francesco Perez-Clavijo; Stephen Wigley; Anuradha Godavarty
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Paper Abstract

Lower extremity ulcers are devastating complications that are still un-recognized. To date, clinicians employ visual inspection of the wound site during its standard 4-week of healing process via monitoring of surface granulation. A novel ultra-portable near-infrared optical scanner (NIROS) has been developed at the Optical Imaging Laboratory that can perform non-contact 2D area imaging of the wound site. From preliminary studies it was observed that the nonhealing wounds had a greater absorption contrast with respect to the normal site, unlike in the healing wounds. Currently, non-contact near-infrared (NIR) imaging studies were carried out on 22 lower extremity wounds at two podiatric clinics, and the sensitivity and specificity of the scanner evaluated. A quantitative optical biometric was developed that differentiates healing from non-healing wounds, based on the threshold values obtained during ROC analysis. In addition, optical images of the wound obtained from weekly imaging studies are also assessed to determine the ability of the device to predict wound healing consistently on a periodic basis. This can potentially impact early intervention in the treatment of lower extremity ulcers when an objective and quantitative wound healing approach is developed. Lastly, the incorporation of MATLAB graphical user interface (GUI) to automate the process of image acquisition, image processing and image analysis realizes the potential of NIROS to perform non-contact and real-time imaging on lower extremity wounds.

Paper Details

Date Published: 7 March 2016
PDF: 6 pages
Proc. SPIE 9699, Optics and Biophotonics in Low-Resource Settings II, 96990S (7 March 2016); doi: 10.1117/12.2212070
Show Author Affiliations
Jiali Lei, Florida International Univ. (United States)
Suset Rodriguez, Florida International Univ. (United States)
Maanasa Jayachandran, Florida International Univ. (United States)
Elizabeth Solis, Florida International Univ. (United States)
Stephanie Gonzalez, Florida International Univ. (United States)
Francesco Perez-Clavijo, Podiatry Care Partners (United States)
Stephen Wigley, Wigley Foot and Ankle LLC (United States)
Anuradha Godavarty, Florida International Univ. (United States)

Published in SPIE Proceedings Vol. 9699:
Optics and Biophotonics in Low-Resource Settings II
David Levitz; Aydogan Ozcan; David Erickson, Editor(s)

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