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Proceedings Paper

Taking advantage of acoustic inhomogeneities in photoacoustic measurements
Author(s): Anabela Da Silva; Charles Handschin; Christophe Riedinger; Julien Piasecki; Serge Mensah; Amélie Litman; Hassan Akhouayri
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Paper Abstract

Photoacoustic offers promising perspectives in probing and imaging subsurface optically absorbing structures in biological tissues. The optical uence absorbed is partly dissipated into heat accompanied with microdilatations that generate acoustic pressure waves, the intensity which is related to the amount of fluuence absorbed. Hence the photoacoustic signal measured offers access, at least potentially, to a local monitoring of the absorption coefficient, in 3D if tomographic measurements are considered. However, due to both the diffusing and absorbing nature of the surrounding tissues, the major part of the uence is deposited locally at the periphery of the tissue, generating an intense acoustic pressure wave that may hide relevant photoacoustic signals. Experimental strategies have been developed in order to measure exclusively the photoacoustic waves generated by the structure of interest (orthogonal illumination and detection). Temporal or more sophisticated filters (wavelets) can also be applied. However, the measurement of this primary acoustic wave carries a lot of information about the acoustically inhomogeneous nature of the medium. We propose a protocol that includes the processing of this primary intense acoustic wave, leading to the quantification of the surrounding medium sound speed, and, if appropriate to an acoustical parametric image of the heterogeneities. This information is then included as prior knowledge in the photoacoustic reconstruction scheme to improve the localization and quantification.

Paper Details

Date Published: 15 March 2016
PDF: 5 pages
Proc. SPIE 9708, Photons Plus Ultrasound: Imaging and Sensing 2016, 97082B (15 March 2016); doi: 10.1117/12.2209549
Show Author Affiliations
Anabela Da Silva, Aix-Marseille Univ. (France)
Charles Handschin, Aix-Marseille Univ. (France)
SATT PACA Corse SAS (France)
Christophe Riedinger, Aix-Marseille Univ. (France)
SATT PACA Corse SAS (France)
Julien Piasecki, SATT PACA Corse SAS (France)
Serge Mensah, Aix-Marseille Univ. (France)
Amélie Litman, Aix-Marseille Univ. (France)
Hassan Akhouayri, Aix-Marseille Univ. (France)

Published in SPIE Proceedings Vol. 9708:
Photons Plus Ultrasound: Imaging and Sensing 2016
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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