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Proceedings Paper

Measuring perfusion with light (Conference Presentation)

Paper Abstract

There is no gold standard test for perfusion evaluation in surgery. Optical Imaging techniques are able to image tissue at high resolution and in real-time. Laser Speckle Contrast Imaging, Optical Coherence Tomography, Sidestream Darkfield and Incident Darkfield all use the interaction of light with tissue to create an image. To test their feasibility and explore validity in a controlled setting, we created a phantom with the optical properties of tissue and microvascular channels of 30-400 micrometer. With a Hamilton Syringe Pump we mimicked blood flow velocities of 0-20 mm/sec. Images of all different modalities at different blood flow velocities were compared in terms of imaging depth, resoluation and hemodynamic parameters.

Paper Details

Date Published: 27 April 2016
PDF: 1 pages
Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 96980O (27 April 2016); doi: 10.1117/12.2209364
Show Author Affiliations
Sanne M. A. Jansen M.D., Academisch Medisch Centrum (Netherlands)
Daniel M. de Bruin, Academisch Medisch Centrum (Netherlands)
Dirk J. Faber, Academisch Medisch Centrum (Netherlands)
Ton G. van Leeuwen, Academisch Medisch Centrum (Netherlands)

Published in SPIE Proceedings Vol. 9698:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Tuan Vo-Dinh; Anita Mahadevan-Jansen; Warren S. Grundfest M.D., Editor(s)

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