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Proceedings Paper

CW fluorescence imaging of tissue-like media in reflectance geometry
Author(s): N. A. Carbone; D. I. Iriarte; J. A. Pomarico; D. Grosenick; R. Macdonald
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Paper Abstract

In the present contribution we investigate images of CW diffusely remitted light registered by a CCD camera imaging a turbid medium containing an absorbent and fluorescent lesion, during illumination by a point-like source. We show that a normalization technique using local background signals reconstructed from experimental data is useful to increase the contrast of both the absorption and the fluorescence channel. Using this technique, results on phantoms are given which demonstrate that lesions with clinically-realistic fluorophore and absorber concentrations can be detected. Results are compared with theoretical calculations as well.

Paper Details

Date Published: 16 July 2015
PDF: 10 pages
Proc. SPIE 9538, Diffuse Optical Imaging V, 95381E (16 July 2015); doi: 10.1117/12.2183473
Show Author Affiliations
N. A. Carbone, IFAS, UNCPBA-CIFICEN (Argentina)
D. I. Iriarte, IFAS, UNCPBA-CIFICEN (Argentina)
J. A. Pomarico, IFAS, UNCPBA-CIFICEN (Argentina)
D. Grosenick, Physikalisch-Technische Bundesanstalt (Germany)
R. Macdonald, Physikalisch-Technische Bundesanstalt (Germany)

Published in SPIE Proceedings Vol. 9538:
Diffuse Optical Imaging V
Hamid Dehghani; Paola Taroni, Editor(s)

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