Acousto-optic imaging (AOI) is an emerging technique in the field of biomedical optics which combines the optical contrast allowed by diffuse optical tomography with the resolution of ultrasound (US) imaging. In this work we report the implementation, for that purpose, of a CMOS smart-pixels sensor dedicated to the real-time analysis of speckle patterns. We implemented a highly sensitive lock-in detection in each pixel in order to extract the tagged photons after an appropriate in-pixel post-processing. With this system we can acquire images in scattering samples with a spatial resolution in the 2mm range, with an integration time compatible with the dynamic of living biological tissue.

Date Published: 13 March 2015
PDF: 7 pages
Proc. SPIE 9403, Image Sensors and Imaging Systems 2015, 940308 (13 March 2015); doi: 10.1117/12.2183112

Published in SPIE Proceedings Vol. 9403:
Image Sensors and Imaging Systems 2015
Ralf Widenhorn; Antoine Dupret, Editor(s)