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Proceedings Paper

Evaluation of an affinity-amplified immunoassay of graphene oxide using surface plasmon resonance biosensors
Author(s): Nan-Fu Chiu; Teng-Yi Huang; Chun-Chuan Kuo
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Paper Abstract

We describe a fundamental study on the plasmonic properties and advanced biosensing mechanisms of functionalized graphene. We discuss a specific design using modified carboxyl groups, which can modulate surface plasmon (SP) coupling and provide an advantage for their binding to the sensing layer with high-performance affinity in an immunological reaction. The functionalized graphene-based surface plasmon resonance (SPR) biosensors have three advantages: high performance, high sensitivity, and excellent molecular kinetic response. In the future, functionalized graphene sheets will make a unique contribution to photonic and SPR diagnosis devices. We wish to highlight the essential characteristics of functionalized graphene-based SPR biosensors to assist researchers in developing and advancing suitable biosensors for unique applications.

Paper Details

Date Published: 5 May 2015
PDF: 7 pages
Proc. SPIE 9506, Optical Sensors 2015, 95061H (5 May 2015); doi: 10.1117/12.2182134
Show Author Affiliations
Nan-Fu Chiu, National Taiwan Normal Univ. (Taiwan)
Teng-Yi Huang, National Taiwan Normal Univ. (Taiwan)
Chun-Chuan Kuo, National Taiwan Normal Univ. (Taiwan)

Published in SPIE Proceedings Vol. 9506:
Optical Sensors 2015
Francesco Baldini; Jiri Homola; Robert A. Lieberman, Editor(s)

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