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Proceedings Paper

In vitro evaluation of ionizing radiation effects in bone tissue by FTIR spectroscopy
Author(s): Denise Maria Zezell; Marcelo Noronha Veloso; Derly Augusto Dias; Rodolfo Politano; Carolina Benetti
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Paper Abstract

We verified the changes promoted by ionizing radiation in bone tissue using FTIR. Samples of bovine bone were irradiated using Cobalt-60 with 0.01kGy, 0.1kGy, 1kGy, 15kGy and 75kGy. The effects of ionizing irradiation on chemical structure of bone, were studied considering the sub-bands of amide I, the crystallinity index and relation of organic and inorganic materials. ATR-FTIR spectroscopy showed changes in organic components and in hydroxyapatite crystals organization. High correlation with statistical significance was observed between (amideIII+collagen)/ ν1,ν3PO4, crystallinity and mechanical properties of the samples.

Paper Details

Date Published: 19 June 2015
PDF: 6 pages
Proc. SPIE 9531, Biophotonics South America, 953118 (19 June 2015); doi: 10.1117/12.2181096
Show Author Affiliations
Denise Maria Zezell, IPEN-CNEN/SP (Brazil)
Marcelo Noronha Veloso, IPEN-CNEN/SP (Brazil)
Derly Augusto Dias, IPEN-CNEN/SP (Brazil)
Rodolfo Politano, IPEN-CNEN/SP (Brazil)
Carolina Benetti, IPEN-CNEN/SP (Brazil)
Univ. Federal do ABC, Santo André (Brazil)


Published in SPIE Proceedings Vol. 9531:
Biophotonics South America
Cristina Kurachi D.D.S.; Katarina Svanberg M.D.; Bruce J. Tromberg; Vanderlei Salvador Bagnato, Editor(s)

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