This work proposes a new method for automatic marking epileptic spike-wave discharges in local field potential (LFP) signals. The method is based on empirical modelling using radial basis functions to approximate dependency of a further state on the current one. Number and type of radial basis functions used are adjusted to data based on statistical criteria. Due to this the method needs only a few manual efforts for its application to new data. The time resolution of the method is close to the sampling interval of the original data, and real time detection is possible. Detection accuracy of the proposed approach is validated analysing the LFP signals obtained using WAG/Rij rats.

Date Published: 19 March 2015
PDF: 8 pages
Proc. SPIE 9448, Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics, 94481R (19 March 2015); doi: 10.1117/12.2179017

Published in SPIE Proceedings Vol. 9448:
Saratov Fall Meeting 2014: Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics
Elina A. Genina; Vladimir L. Derbov; Kirill V. Larin; Dmitry E. Postnov; Valery V. Tuchin, Editor(s)