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Proceedings Paper

Intelligent refractive index detector for capillary electrophoresis
Author(s): Vasily L. Kasyutich; Igor I. Mahnach
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Paper Abstract

A laser diode refractive index detector is presented for high performance capillary electrophoresis device. An operational principle of the detector is based on off-axis capillary focusing of the laser beam to the round cross-section capillary and on the detection of interference fringe shifts induced by the refractive index solvent changes in the capillary bore. A principle of an automatic adjustment of the laser diode and a photoreceiver is described for the capillary and solvent replacements. A sensitivity and a linear dynamic range are represented for capillaries with i.d. 0.075 mm, 0.1 mm and o.d. 0.31 mm, 0.17 mm, respectively.

Paper Details

Date Published: 23 June 1995
PDF: 9 pages
Proc. SPIE 2208, Refractometry, (23 June 1995); doi: 10.1117/12.213173
Show Author Affiliations
Vasily L. Kasyutich, Institute of Molecular and Atomic Physics (Belarus)
Igor I. Mahnach, SPE/Mitana (Belarus)


Published in SPIE Proceedings Vol. 2208:
Refractometry
Maksymilian Pluta; Mariusz Szyjer, Editor(s)

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