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Proceedings Paper

Pulsed laser ablation of tissue: surface vaporization or thermal explosion?
Author(s): Vasan Venugopalan
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Paper Abstract

In this paper we discuss the effects of laser-induced stresses and tissue chromophore targeting on the mechanism and dynamics of pulsed laser ablation. We argue that larger pulse durations and optical absorption coefficients reduce the contribution of photomechanical effects to the onset of material removal. Further we argue that if the structural integrity of the tissue extra-cellular matrix (ECM) is not compromised during irradiation, the ablation process will necessarily be explosive even if the heated tissue volume is allowed to mechanically equilibrate to the laser-induced stressed during irradiation. However, if the tissue is not inertially confined and the ECM is compromised during irradiation, the material removal is consistent with a process of rapid surface vaporization.

Paper Details

Date Published: 22 May 1995
PDF: 6 pages
Proc. SPIE 2391, Laser-Tissue Interaction VI, (22 May 1995); doi: 10.1117/12.209881
Show Author Affiliations
Vasan Venugopalan, Wellman Labs. of Photomedicine, Massachusetts General Hospital, Harvard Medical School (United States)
Massachusetts Institute of Technology (United States)

Published in SPIE Proceedings Vol. 2391:
Laser-Tissue Interaction VI
Steven L. Jacques, Editor(s)

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