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Proceedings Paper

Characterization of products of excimer laser ablation of collagen
Author(s): Marwood N. Ediger; D. W. Hahn; George H. Pettit M.D.
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Paper Abstract

The presence of hydroxyl radicals in the ArF excimer ablation sites in bovine corneal tissue has been investigated by laser-induced fluorescence and Raman spectroscopy. Raman spectroscopy has also been applied to examine the time-resolved temperature of the water component of the ablation site as well as the spatially selective measurement of surface desiccation. Results indicate that the hydroxyl radical is not generate in abundance during the ablation process. Also, Raman monitoring of the ablation site demonstrates no detectable heating during ArF irradiation, while elevated temperatures are observed following exposure of the corneal surface to a Er:YAG laser. Finally, comparison of C-H and O-H Raman bands shows potential utility as a spatially selective means for monitoring tissue hydration.

Paper Details

Date Published: 22 May 1995
PDF: 5 pages
Proc. SPIE 2393, Ophthalmic Technologies V, (22 May 1995); doi: 10.1117/12.209832
Show Author Affiliations
Marwood N. Ediger, Ctr. for Devices and Radiological Health/FDA (United States)
D. W. Hahn, Sandia National Labs. (United States)
George H. Pettit M.D., Ctr. for Devices and Radiological Health/FDA (United States)

Published in SPIE Proceedings Vol. 2393:
Ophthalmic Technologies V
Jean-Marie Parel; Qiushi Ren; Karen Margaret Joos M.D., Editor(s)

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