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Proceedings Paper

Initial results from a prototype whole-body photon-counting computed tomography system
Author(s): Z. Yu; S. Leng; S. M. Jorgensen; Z. Li; R. Gutjahr; B. Chen; X. Duan; A. F. Halaweish; L. Yu; E. L. Ritman; C. H. McCollough
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Paper Abstract

X-ray computed tomography (CT) with energy-discriminating capabilities presents exciting opportunities for increased dose efficiency and improved material decomposition analyses. However, due to constraints imposed by the inability of photon-counting detectors (PCD) to respond accurately at high photon flux, to date there has been no clinical application of PCD-CT. Recently, our lab installed a research prototype system consisting of two x-ray sources and two corresponding detectors, one using an energy-integrating detector (EID) and the other using a PCD. In this work, we report the first third-party evaluation of this prototype CT system using both phantoms and a cadaver head. The phantom studies demonstrated several promising characteristics of the PCD sub-system, including improved longitudinal spatial resolution and reduced beam hardening artifacts, relative to the EID sub-system. More importantly, we found that the PCD sub-system offers excellent pulse pileup control in cases of x-ray flux up to 550 mA at 140 kV, which corresponds to approximately 2.5×1011 photons per cm2 per second. In an anthropomorphic phantom and a cadaver head, the PCD sub-system provided image quality comparable to the EID sub-system for the same dose level. Our results demonstrate the potential of the prototype system to produce clinically-acceptable images in vivo.

Paper Details

Date Published: 18 March 2015
PDF: 7 pages
Proc. SPIE 9412, Medical Imaging 2015: Physics of Medical Imaging, 94120W (18 March 2015); doi: 10.1117/12.2082739
Show Author Affiliations
Z. Yu, Mayo Clinic (United States)
S. Leng, Mayo Clinic (United States)
S. M. Jorgensen, Mayo Clinic (United States)
Z. Li, Mayo Clinic (United States)
R. Gutjahr, Siemens Medical Solutions USA, Inc. (United States)
B. Chen, Mayo Clinic (United States)
X. Duan, Mayo Clinic (United States)
A. F. Halaweish, Siemens Medical Solutions USA, Inc. (United States)
L. Yu, Mayo Clinic (United States)
E. L. Ritman, Mayo Clinic (United States)
C. H. McCollough, Mayo Clinic (United States)

Published in SPIE Proceedings Vol. 9412:
Medical Imaging 2015: Physics of Medical Imaging
Christoph Hoeschen; Despina Kontos, Editor(s)

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