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Proceedings Paper

Microvascular changes during acne lesion initiation and scarring within human skin is revealed in vivo using optical microangiography
Author(s): Utku Baran; Yuandong Li; Woo J. Choi; Ruikang K. Wang
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Paper Abstract

Acne is a common skin disease in society and often leads to scarring. In this paper, we demonstrate the capabilities of swept-source optical coherence tomography (SS-OCT) in detecting specific features of acne lesion initiation and scarring on human facial skin in vivo over 30 days. Optical microangiography (OMAG) technique made it possible to image 3D tissue microvasculature changes up to 1 mm depth in vivo without the need of exogenous contrast agents in ~10 seconds. The presented results show promise to facilitate clinical trials of treatment and prognosis of acne vulgaris by detecting cutaneous microvasculature and structural changes within human skin in vivo.

Paper Details

Date Published: 26 February 2015
PDF: 4 pages
Proc. SPIE 9303, Photonic Therapeutics and Diagnostics XI, 93030J (26 February 2015); doi: 10.1117/12.2082717
Show Author Affiliations
Utku Baran, Univ. of Washington (United States)
Yuandong Li, Univ. of Washington (United States)
Woo J. Choi, Univ. of Washington (United States)
Ruikang K. Wang, Univ. of Washington (United States)

Published in SPIE Proceedings Vol. 9303:
Photonic Therapeutics and Diagnostics XI
Hyun Wook Kang; Brian J. F. Wong M.D.; Melissa C. Skala; Bernard Choi; Guillermo J. Tearney M.D.; Andreas Mandelis; Nikiforos Kollias; Kenton W. Gregory M.D.; Mark W. Dewhirst D.V.M.; Justus F. Ilgner M.D.; Alfred Nuttal; Haishan Zeng; Laura Marcu; Claus-Peter Richter, Editor(s)

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