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Proceedings Paper

Segmentation of the whole breast from low-dose chest CT images
Author(s): Shuang Liu; Mary Salvatore; David F. Yankelevitz; Claudia I. Henschke; Anthony P. Reeves
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Paper Abstract

The segmentation of whole breast serves as the first step towards automated breast lesion detection. It is also necessary for automatically assessing the breast density, which is considered to be an important risk factor for breast cancer. In this paper we present a fully automated algorithm to segment the whole breast in low-dose chest CT images (LDCT), which has been recommended as an annual lung cancer screening test. The automated whole breast segmentation and potential breast density readings as well as lesion detection in LDCT will provide useful information for women who have received LDCT screening, especially the ones who have not undergone mammographic screening, by providing them additional risk indicators for breast cancer with no additional radiation exposure. The two main challenges to be addressed are significant range of variations in terms of the shape and location of the breast in LDCT and the separation of pectoral muscles from the glandular tissues. The presented algorithm achieves robust whole breast segmentation using an anatomy directed rule-based method. The evaluation is performed on 20 LDCT scans by comparing the segmentation with ground truth manually annotated by a radiologist on one axial slice and two sagittal slices for each scan. The resulting average Dice coefficient is 0.880 with a standard deviation of 0.058, demonstrating that the automated segmentation algorithm achieves results consistent with manual annotations of a radiologist.

Paper Details

Date Published: 20 March 2015
PDF: 11 pages
Proc. SPIE 9414, Medical Imaging 2015: Computer-Aided Diagnosis, 94140I (20 March 2015); doi: 10.1117/12.2082410
Show Author Affiliations
Shuang Liu, Cornell Univ. (United States)
Mary Salvatore, Icahn School of Medicine at Mount Sinai (United States)
David F. Yankelevitz, Icahn School of Medicine at Mount Sinai (United States)
Claudia I. Henschke, Icahn School of Medicine at Mount Sinai (United States)
Anthony P. Reeves, Cornell Univ. (United States)

Published in SPIE Proceedings Vol. 9414:
Medical Imaging 2015: Computer-Aided Diagnosis
Lubomir M. Hadjiiski; Georgia D. Tourassi, Editor(s)

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