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Proceedings Paper

3D in vivo imaging of rat hearts by high frequency ultrasound and its application in myofiber orientation wrapping
Author(s): Xulei Qin; Silun Wang; Ming Shen; Xiaodong Zhang; Stamatios Lerakis; Mary B. Wagner; Baowei Fei
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Paper Abstract

Cardiac ultrasound plays an important role in the imaging of hearts in basic cardiovascular research and clinical examinations. 3D ultrasound imaging can provide the geometry or motion information of the heart. Especially, the wrapping of cardiac fiber orientations to the ultrasound volume could supply useful information on the stress distributions and electric action spreading. However, how to acquire 3D ultrasound volumes of the heart of small animals in vivo for cardiac fiber wrapping is still a challenging problem. In this study, we provide an approach to acquire 3D ultrasound volumes of the rat hearts in vivo. The comparison between both in vivo and ex vivo geometries indicated 90.1% Dice similarity. In this preliminary study, the evaluations of the cardiac fiber orientation wrapping errors were 24.7° for the acute angle error and were 22.4° for the inclination angle error. This 3D ultrasound imaging and fiber orientation estimation technique have potential applications in cardiac imaging.

Paper Details

Date Published: 17 March 2015
PDF: 7 pages
Proc. SPIE 9419, Medical Imaging 2015: Ultrasonic Imaging and Tomography, 941906 (17 March 2015); doi: 10.1117/12.2082326
Show Author Affiliations
Xulei Qin, Emory Univ. (United States)
Silun Wang, Emory Univ. (United States)
Ming Shen, Emory Univ. (United States)
Xiaodong Zhang, Emory Univ. (United States)
Stamatios Lerakis, Emory Univ. (United States)
Mary B. Wagner, Emory Univ. (United States)
Baowei Fei, Emory Univ. (United States)
Georgia Institute of Technology (United States)

Published in SPIE Proceedings Vol. 9419:
Medical Imaging 2015: Ultrasonic Imaging and Tomography
Johan G. Bosch; Neb Duric, Editor(s)

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