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Proceedings Paper

Characterization of neonatal patients with intraventricular hemorrhage using 3D ultrasound cerebral ventricle volumes
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Paper Abstract

One of the major non-congenital cause of neurological impairment among neonates born very preterm is intraventricular hemorrhage (IVH) - bleeding within the lateral ventricles. Most IVH patients will have a transient period of ventricle dilation that resolves spontaneously. However, those patients most at risk of long-term impairment are those who have progressive ventricle dilation as this causes macrocephaly, an abnormally enlarged head, then later causes increases intracranial pressure (ICP). 2D ultrasound (US) images through the fontanelles of the patients are serially acquired to monitor the progression of the ventricle dilation. These images are used to determine when interventional therapies such as needle aspiration of the built up CSF might be indicated for a patient. Initial therapies usually begin during the third week of life. Such interventions have been shown to decrease morbidity and mortality in IVH patients; however, this comes with risks of further hemorrhage or infection; therefore only patients requiring it should be treated. Previously we have developed and validated a 3D US system to monitor the progression of ventricle volumes (VV) in IVH patients. This system has been validated using phantoms and a small set of patient images. The aim of this work is to determine the ability of 3D US generated VV to categorize patients into those who will require interventional therapies, and those who will have spontaneous resolution. Patients with higher risks could therefore be monitored better, by re-allocating some of the resources as the low risks infants would need less monitoring.

Paper Details

Date Published: 17 March 2015
PDF: 7 pages
Proc. SPIE 9419, Medical Imaging 2015: Ultrasonic Imaging and Tomography, 941905 (17 March 2015); doi: 10.1117/12.2081964
Show Author Affiliations
Jessica Kishimoto, Univ. of Western Ontario (Canada)
Aaron Fenster, Univ. of Western Ontario (Canada)
David S. C. Lee, Univ. of Western Ontario (Canada)
London Health Sciences Ctr. (Canada)
Sandrine de Ribaupierre M.D., Univ. of Western Ontario (Canada)
London Health Sciences Ctr. (Canada)

Published in SPIE Proceedings Vol. 9419:
Medical Imaging 2015: Ultrasonic Imaging and Tomography
Johan G. Bosch; Neb Duric, Editor(s)

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