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Proceedings Paper

Light emitting diode (LED) system for photodynamic therapy
Author(s): Greg Graham; A. Charles Lytle; Brian K. Dalton; Dale D. Severson; Jon A. Warner; Greta M. Garbo; Greg B. Rocklin; Daniel R. Doiron
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Paper Abstract

Photodynamic therapy, PDT, has mainly been done clinically using laser systems. The use of lasers to treat cutaneous lesions is not necessary. In order to provide a more efficient and cost effective light source for the PDT treatment of cutaneous lesions, a clinical based light emitting diode (LED) system has been developed. The system include a tight density packing of AlGaAs high-brightness LEDs to produce incident irradiance values up to 200 MW/cm2. Initial systems have wavelengths of 665 nm and exhibit a bandwidth of 25 nm, FWHM. Other wavelengths are also possible. The system includes on-line dosimetry through an isotropic probe to permit the use to simply choose a dose, J/cm2. the system has been tested against a KTP/dye laser for the photosensitizer SnET2 to determine its equivalence to a monochromatic source.

Paper Details

Date Published: 1 May 1995
PDF: 6 pages
Proc. SPIE 2392, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IV, (1 May 1995); doi: 10.1117/12.208175
Show Author Affiliations
Greg Graham, PDT Systems, Inc. (United States)
A. Charles Lytle, PDT Systems, Inc. (United States)
Brian K. Dalton, PDT Systems, Inc. (United States)
Dale D. Severson, PDT Systems, Inc. (United States)
Jon A. Warner, PDT Systems, Inc. (United States)
Greta M. Garbo, PDT Pharmaceuticals, Inc. (United States)
Greg B. Rocklin, PDT Pharmaceuticals, Inc. (United States)
Daniel R. Doiron, PDT Systems, Inc. (United States)

Published in SPIE Proceedings Vol. 2392:
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IV
Thomas J. Dougherty, Editor(s)

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