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Proceedings Paper

Microstructure analysis of the pulmonary acinus using a synchrotron radiation CT
Author(s): Y. Tokumoto; K. Minami; Y. Kawata; N. Niki; K. Umetani; Y. Nakano; H. Sakai; H. Ohmatsu; H. Itoh
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Paper Abstract

Conversion of images at micro level of normal and with very early stage disease of the lung and quantitative analysis of morphology on CT image can contribute to the chest image diagnosis to the next generation. Previous, anatomy and pathology analysis of pulmonary lobule have been conducted to better understand the CT image of peripheral lung tissue disease. However, it is difficult to figure out three-dimensional (3D) conformation because of analyzing at the slice image. The purpose of this study is a 3D microstructual and quantitative analyses of pulmonary acinus with spatial resolution in the range of several micrometers by using a synchrotron radiation micro CT (SRμCT). In this paper, we present a semi-automatic method for segmenting the secondary pulmonary lobule into acinus or subacinus and extracting small vessel in human acinus imaged by the SRμCT.

Paper Details

Date Published: 17 March 2015
PDF: 7 pages
Proc. SPIE 9417, Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging, 94172P (17 March 2015); doi: 10.1117/12.2081357
Show Author Affiliations
Y. Tokumoto, The Univ. of Tokushima (Japan)
K. Minami, The Univ. of Tokushima (Japan)
Y. Kawata, The Univ. of Tokushima (Japan)
N. Niki, The Univ. of Tokushima (Japan)
K. Umetani, Japan Synchrotron Radiation Research Institute (Japan)
Y. Nakano, Shiga Univ. of Medical Science (Japan)
H. Sakai, Hyogo Prefectural Amagasaki Hospital (Japan)
H. Ohmatsu, National Cancer Ctr. Hospital East (Japan)
H. Itoh, Univ. of Fukui Biomedical Research Ctr. (Japan)

Published in SPIE Proceedings Vol. 9417:
Medical Imaging 2015: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Robert C. Molthen, Editor(s)

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