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Proceedings Paper

Multivariate optical computing for fluorochrome discrimination
Author(s): Ryan J. Priore; Joseph A. Swanstrom
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Paper Abstract

Multivariate Optical Elements (MOEs) are thin-film devices that encode a broad band, spectroscopic pattern allowing a simple broadband detector to generate a highly sensitive and specific detection for a target analyte. MOE filter sets are capable of sensing projections of the original sparse spectroscopic space enabling a small set of MOEs to discriminate a multitude of target analytes. This presentation will summarize the design and fabrication of compressed detection MOE filter sets for detecting multiple fluorochromes simultaneously with strong spectroscopic interference as well as comparing the detection performance of the MOE sensor with traditional optical band pass filter methodologies.

Paper Details

Date Published: 9 March 2015
PDF: 8 pages
Proc. SPIE 9332, Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics, 933212 (9 March 2015); doi: 10.1117/12.2080996
Show Author Affiliations
Ryan J. Priore, CIRTEMO (United States)
Joseph A. Swanstrom, CIRTEMO (United States)

Published in SPIE Proceedings Vol. 9332:
Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics
Gerard L. Coté, Editor(s)

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