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Proceedings Paper

Compact Raman needle probe with fine needle aspiration biopsy for solid tissues
Author(s): Jianfeng Wang; Wei Zheng; Zhiwei Huang
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Paper Abstract

Raman spectroscopy represents a label-free vibrational spectroscopic technique for studying the biochemical and biomolecular compositions of human body. Raman probe is a key component to facilitate the in vivo diagnosis by using Raman spectroscopy. We investigated a compact Raman needle probe design to be integrated into a device that can also take biopsies of solid tissues for cytological assessment, enabling concurrent Raman spectroscopic interrogation and fine needle aspiration biopsy with a single needle penetration. We described the fabrication of the Raman needle probe and its assembly with the biopsy device. Example Raman spectra of various solid tissues are given.

Paper Details

Date Published: 5 March 2015
PDF: 7 pages
Proc. SPIE 9317, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV, 931703 (5 March 2015); doi: 10.1117/12.2080944
Show Author Affiliations
Jianfeng Wang, National Univ. of Singapore (Singapore)
Wei Zheng, National Univ. of Singapore (Singapore)
Zhiwei Huang, National Univ. of Singapore (Singapore)

Published in SPIE Proceedings Vol. 9317:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV
Israel Gannot, Editor(s)

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