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Proceedings Paper

Application of optical coherence tomography attenuation imaging for quantification of optical properties in medulloblastoma
Author(s): Barry Vuong; Patryk Skowron; Tim-Rasmus Kiehl M.D.; Matthew Kyan; Livia Garzia; Helen Genis; Cuiru Sun; Michael D. Taylor M.D.; Victor X. D. Yang M.D.
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Paper Abstract

The hemodynamic environment is known to play a crucial role in the progression, rupture, and treatment of intracranial aneurysms. Currently there is difficulty assessing and measuring blood flow profiles in vivo. An emerging high resolution imaging modality known as split spectrum Doppler optical coherence tomography (ssDOCT) has demonstrated the capability to quantify hemodynamic patterns as well as arterial microstructural changes. In this study, we present a novel in vitro method to acquire precise blood flow patterns within a patient- specific aneurysm silicone flow models using ssDOCT imaging. Computational fluid dynamics (CFD) models were generated to verify ssDOCT results.

Paper Details

Date Published: 2 March 2015
PDF: 4 pages
Proc. SPIE 9312, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIX, 93122Z (2 March 2015); doi: 10.1117/12.2080642
Show Author Affiliations
Barry Vuong, Ryerson Univ. (Canada)
Patryk Skowron, Ryerson Univ. (Canada)
Hospital for Sick Children (Canada)
Tim-Rasmus Kiehl M.D., Univ. Health Network (Canada)
Univ. of Toronto (Canada)
Matthew Kyan, Ryerson Univ. (Canada)
Livia Garzia, Univ. of Toronto (Canada)
Hospital for Sick Children (Canada)
Helen Genis, Ryerson Univ. (Canada)
Cuiru Sun, Ryerson Univ. (Canada)
Michael D. Taylor M.D., Ryerson Univ. (Canada)
Hospital for Sick Children (Canada)
Univ. of Toronto (Canada)
Victor X. D. Yang M.D., Ryerson Univ. (Canada)
Univ. of Toronto (Canada)
Sunnybrook Research Institute (Canada)

Published in SPIE Proceedings Vol. 9312:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIX
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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