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Proceedings Paper

Multiple-antenna microwave ablation: analysis of non-parallel antenna implants
Author(s): Souvick Mukherjee; Sergio Curto; Nathan Albin; Bala Natarajan; Punit Prakash
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Paper Abstract

Microwave ablation is a minimally invasive modality increasingly being used for thermal treatment of cancer in various organs. During ablation procedures, treatment planning is typically restricted to vendor specifications of expected ablation zone volumes based on experiments in unperfused ex vivo tissues, presuming parallel insertion of antennas. However, parallel antenna implants are not always clinically possible due to the restricted control of flexible antennas and presence of intervening organs. This paper aims to quantify the effect of non-parallel antenna implants on the ablation volume. 3D electromagnetic-bioheat transfer models were implemented to analyze ablation zone profiles created by dual antenna arrays. Parallel and non-parallel implants spaced 10-25 mm with antenna tips deviated to create converging or diverging configurations were analyzed. Volumetric Dice Similarity Coefficients (DSC) were calculated to compare ablation zone volumes for parallel and non-parallel configuration. Antenna tip displacements of 3 mm/antenna yielded an average DSC of 0.78. Tip displacements of 5 mm/antenna yielded a DSC of 0.78 and 0.64 for 15 mm and 20 mm antenna spacing, respectively. For ablation with dipole antennas as the frequency of operation decreases from 2.45 GHz to 915 MHz the similarity between the ablation zones for parallel and angled cases increased significantly. In conclusion, ablation volumes with non-parallel antenna implants may differ significantly from the parallel configuration. Patient-specific treatment planning tools may provide more accurate predictions of 3D-ablation volumes based on imaging data of actual implanted antenna configurations. Methods to compare ablation zone volumes incorporating uncertainty in antenna positions and experimental results to validate the numerical modelling are also presented.

Paper Details

Date Published: 12 March 2015
PDF: 11 pages
Proc. SPIE 9326, Energy-based Treatment of Tissue and Assessment VIII, 93260U (12 March 2015); doi: 10.1117/12.2080349
Show Author Affiliations
Souvick Mukherjee, Kansas State Univ. (United States)
Sergio Curto, Kansas State Univ. (United States)
Nathan Albin, Kansas State Univ. (United States)
Bala Natarajan, Kansas State Univ. (United States)
Punit Prakash, Kansas State Univ. (United States)

Published in SPIE Proceedings Vol. 9326:
Energy-based Treatment of Tissue and Assessment VIII
Thomas P. Ryan, Editor(s)

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