Minimally invasive surgeries are approaching 50% of all interventional procedures in the US, yet there is a lack of objective tools to assist surgeons in this limited sensing environment. In this preliminary work, we present a novel proof of concept implementation of Single Snapshot of Optical Properties (SSOP) imaging through a rigid endoscope. In this embodiment, a stereo rigid endoscope is used with one channel to project spatially modulated illumination and the second channel to image the diffuse reflectance onto a CCD sensor. Optical property maps are then obtained for various tissue simulating phantoms and validated against standard wide-field spatial frequency domain imaging (SFDI). The implementation of endoscopic SSOP creates potential for practical use of endoscopic tissue constituent quantification. The results show good agreement (within 5%) for endoscopic SSOP versus wide-field SFDI. However, endoscopic SSOP acquisition allows for video-rate imaging, limited only by the exposure time of image capture. These results show promise for an objective endoscopic tissue viability assessment tool being achievable in a clinical setting.

Date Published: 13 March 2015
PDF: 5 pages
Proc. SPIE 9313, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII, 93130P (13 March 2015); doi: 10.1117/12.2080227

Published in SPIE Proceedings Vol. 9313:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest M.D.; Quan Liu, Editor(s)