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Proceedings Paper

Estimation of elastic parameters of ovarian tissue using phase stabilized swept source optical-coherence tomography
Author(s): Sreyankar Nandy; Tianheng Wang; Hassan Salehi; Melinda Sanders; Molly Brewer; Quing Zhu
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Paper Abstract

We have estimated the micro-mechanical properties of ovarian tissue using phase-sensitive swept source optical coherence tomography. Ovary samples were mechanically excited by periodical vibration of an ultrasound transducer. The displacement and strain of the tissues were calculated during loading. Significant difference in strain was observed between the normal and malignant ovary groups, which indicates much softer and heterogeneous tissue structure for malignant ovaries. The initial results show that the phase sensitive swept source optical coherence elastography (OCE) can be an effective tool for characterization of stiffness and other micro-mechanical properties of normal and malignant ovarian tissue.

Paper Details

Date Published: 6 March 2015
PDF: 6 pages
Proc. SPIE 9327, Optical Elastography and Tissue Biomechanics II, 93270D (6 March 2015); doi: 10.1117/12.2080202
Show Author Affiliations
Sreyankar Nandy, Univ. of Connecticut (United States)
Tianheng Wang, Univ. of Connecticut (United States)
Hassan Salehi, Univ. of Connecticut (United States)
Melinda Sanders, Univ. of Connecticut Health Center (United States)
Molly Brewer, Univ. of Connecticut (United States)
Univ. of Connecticut Health Center (United States)
Quing Zhu, Univ. of Connecticut (United States)
Univ. of Connecticut Health Center (United States)

Published in SPIE Proceedings Vol. 9327:
Optical Elastography and Tissue Biomechanics II
Kirill V. Larin; David D. Sampson, Editor(s)

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