Share Email Print

Proceedings Paper

Co-focused ultrasound and optical coherence elastography system for the study of age-related changes of biomechanical properties of crystalline lens in rabbit eyes
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

In this study, we utilize a confocal ultrasound and phase-sensitive optical coherence elastography (OCE) system to assess age-related changes in biomechanical properties of the crystalline lens in intact rabbit eyes in situ. Lowamplitude elastic deformations, induced on the surface of the lens by localized acoustic radiation force, were measured using phase-sensitive OCT. The results demonstrate that the displacements induced in young rabbit lenses are significantly larger than those in the mature lenses. Temporal analyses of the elastic waves are also demonstrated significant difference between young and old lenses, indicating that the stiffness of lens increases with the age. These results demonstrate possibility of OCE for completely noninvasive analysis and quantification of lens biomechanical properties, which could be used in many clinical and basic science applications such as surgeries and studies on lens physiology and function.

Paper Details

Date Published: 12 March 2015
PDF: 7 pages
Proc. SPIE 9307, Ophthalmic Technologies XXV, 930716 (12 March 2015); doi: 10.1117/12.2079532
Show Author Affiliations
Chen Wu, Univ. of Houston (United States)
Zhaolong Han, Univ. of Houston (United States)
Shang Wang, Univ. of Houston (United States)
Baylor College of Medicine (United States)
Jiasong Li, Univ. of Houston (United States)
Manmohan Singh, Univ. of Houston (United States)
Chih-hao Liu, Univ. of Houston (United States)
Salavat Aglyamov, The Univ. of Texas at Austin (United States)
Stanislav Emelianov, The Univ. of Texas at Austin (United States)
Fabrice Manns, Bascom Palmer Eye Institute, Univ. of Miami School of Medicine (United States)
Univ. of Miami College of Engineering (United States)
Kirill V. Larin, Univ. of Houston (United States)
Baylor College of Medicine (United States)

Published in SPIE Proceedings Vol. 9307:
Ophthalmic Technologies XXV
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?